The sort-of-sequel to Knocked Up.
It follows the other couple from that movie, Pete & Debbie, as they hit 40-years-old and suffer a marital crisis, financial problems, a daughter going through puberty and other mid-life problems.
It's pretty much sitcom material from Judd Apatow with slightly more interesting characters, though it's quite obvious in the dialogue what was scripted and what was ad-libbed by the actors. It also makes a mistake of marketing itself as a "sequel" to Knocked Up (qv), but doesn't even have any true reference to events from that movie, nor does it feature the characters played by Katherine Heigl and Seth Rogen. Instead it features cameos from Jason Segel, John Lithgow, Megan Fox and others.
As a standalone comedy, it's reasonably enjoyable as a witty attempt to mirror the trials and tribulations of a real-life relationship, but it could have done with being half-an-hour shorter.