After an African monkey carrying a fatal virus stows away to America, a deadly epidemic spreads around a small town which the US government quarantine whilst medical officers work around the clock to find a cure.
Outbreak is a good example of a generally good idea gone sour when Hollywood studios throw lots of money at it. The story gets more and more ridiculous as the film progresses, not helped by a pantomime bad guy character played by Donald Sutherland.
Dustin Hoffman and the rest of the cast are generally good with underwritten characters & there's very good use of cinematography from Michael Ballhaus, but aside from this, it's all rather average and incredibly unfeasible.